Latest DePIN News

In a significant advancement for weather monitoring and disaster preparedness, WeatherXM, a decentralized weather network, has partnered with DePIN South Africa to deploy 320 hyperlocal weather stations across various regions in South Africa within just 90 days. This initiative aims to provide municipalities, utilities, and businesses with accurate, audited street-level weather observations, transforming unpredictable weather patterns into actionable data. The deployment is particularly crucial given South Africa's climate challenges, which include flash floods, heatwaves, and droughts that strain essential services and infrastructure. The WeatherXM and DePIN SA collaboration focuses on integrating weather stations into a grassroots network that spans rooftops, masts, and community locations, especially in flood-prone and agricultural areas. Local teams conducted thorough assessments to ensure optimal placement and functionality of the stations, which utilize WeatherXM’s Proof-of-Quality method for calibration and telemetry. Once operational, the data collected is routed to WeatherXM’s APIs and Pro dashboards, allowing real-time monitoring by municipal teams, logistics operators, and insurers to enhance their operational readiness and response strategies. As the network transitions to daily use, the impact of these hyperlocal observations is already evident. Public sector teams are leveraging local rainfall and heat data to improve planning and coordination for flood and heat events. Energy and utility operators are using the information to anticipate outages and maintain grid stability, while insurers are incorporating these observations into parametric triggers, streamlining claims processes. This innovative approach underscores the importance of ground-truth data in decision-making, with WeatherXM's CEO emphasizing the need for rapid rollouts and measurable results to enhance resilience in the face of climate unpredictability.

Aethir, a leading provider of decentralized AI compute, has announced a significant partnership with Predictive Oncology, a pioneer in AI-driven drug discovery. This collaboration will see Predictive Oncology amass a strategic compute reserve of $344.4 million, specifically designed to acquire and stake ATH, Aethir's network token. The initiative, led by DNA Fund and supported by BTIG, marks a groundbreaking moment as it is the first instance of a Nasdaq-listed company actively managing tokens from a decentralized physical infrastructure network. This move aims to address the GPU shortage that has been hampering scientific advancements across various fields, including pharmaceutical research and climate modeling. The partnership is expected to enhance Predictive Oncology's capabilities in training AI models that analyze extensive genomic and patient datasets. The high costs and limited availability of centralized cloud providers have made it difficult for companies in oncology to access the necessary high-performance compute resources. Raymond Vennare, CEO of Predictive Oncology, emphasized that this partnership not only solidifies their core business but also opens up new growth opportunities through their digital asset treasury strategy. DNA Holdings Venture, Inc. will act as the strategic advisor for this initiative, connecting institutional capital with Aethir's GPU infrastructure. Aethir's decentralized marketplace is designed to source and manage enterprise-grade GPU supply, offering significant cost savings compared to traditional providers. With over $150 million in verifiable annual recurring revenue, Aethir has already delivered 1.16 billion compute hours, demonstrating its capacity to drive faster AI innovation and democratize access to GPU resources. By accumulating and staking ATH, Predictive Oncology aims to bolster the security and decentralization of the Aethir network, allowing institutional investors to engage in its growth without direct token custody. This partnership not only highlights the potential of decentralized infrastructure in AI but also sets a precedent for future collaborations in the field.

The U.S. Securities and Exchange Commission (SEC) has issued a significant "no action" letter regarding the DEPIN (decentralized physical infrastructure networks) sector, specifically addressing the distribution of Double Zero's 2Z token. This letter indicates that the SEC will not pursue enforcement actions against the token's distribution, affirming that the programmatic transfers described do not fall under the registration requirements of Section 5 of the Securities Act. This clarity is expected to encourage participation in DEPIN networks without the looming concern of regulatory repercussions. Double Zero operates a low-latency DEPIN that utilizes underutilized physical fiber to enhance blockchain performance by mitigating traditional network frictions. In exchange for their contributions, participants in the network will receive the 2Z token. SEC Commissioner Hester Peirce emphasized that DEPIN tokens should be viewed as incentives rather than investment contracts, suggesting that classifying them as securities could hinder the growth of decentralized service networks. This perspective aligns with the SEC's recent trend of categorizing certain crypto tokens as non-securities, which has positively impacted market sentiment. Following the SEC's announcement, the DEPIN sector experienced a notable surge, with the overall market size increasing by 3% to reach $34 billion. Several projects, including Zebec Network, Helium IOT, and Dynex, saw significant gains, reflecting the optimism surrounding regulatory clarity. This marks the third instance where the SEC has classified a category of crypto tokens as non-securities, following similar decisions for proof-of-work and proof-of-stake systems earlier this year. As Double Zero prepares to transition from testnet to mainnet, the regulatory environment appears increasingly favorable for DEPIN initiatives.

Karrier One, a leader in decentralized telecom infrastructure, has announced a significant partnership with Iridium Communications Inc. This collaboration aims to integrate Iridium's NTN Direct IoT capabilities into the Karrier One ecosystem, allowing for enhanced connectivity in remote and inaccessible locations. According to Samer Bishay, CEO of Karrier One, this partnership will enable deployers to connect sensors and devices globally, eliminating the need for local base stations. This development is particularly crucial for applications such as environmental monitoring and asset tracking in areas where terrestrial networks are unavailable. The integration of Karrier One's decentralized network model with Iridium's low-Earth orbit satellites offers several advantages. Deployers can achieve instant global reach for narrowband IoT devices, ensuring connectivity across land, sea, and air. Additionally, the collaboration allows for zero infrastructure deployment, enabling users to focus on their applications rather than on building physical towers. This resilient machine-to-machine (M2M) communication is ideal for critical use cases, including maritime tracking and environmental sensing, providing seamless network integration through the Karrier One platform. This partnership reflects a shared vision of redefining connectivity beyond geographical limitations. The MOU will lead to a bilateral agreement that will detail the technical integration and commercial rollout of their collaboration. As Karrier One continues to innovate in decentralized telecommunications, this partnership with Iridium positions them to empower innovators to deploy IoT solutions anywhere on Earth, ensuring reliability and extensive reach in the process.

In a remarkable collaboration, BLCK IoT and WeatherXM have successfully installed 130 hyperlocal weather stations across rural and peri-urban Kenya within just 45 days. This initiative has led to significant improvements in agricultural productivity, with farm yields increasing by 18% and water usage reduced by 22%. Additionally, the enhanced data collection has improved flood modeling accuracy by over 30%. The deployment of these weather stations provides crucial local observations that empower farmers, insurers, researchers, and local governments to make informed decisions regarding crop planting, insurance claims, and flood preparedness. The need for reliable weather data in Kenya has become increasingly critical due to the unpredictable nature of seasonal rains, which has made agricultural planning more challenging. Droughts and flash floods have become more common, leading to potential losses for smallholder farmers who may misjudge the timing for planting or watering their crops. The partnership between BLCK IoT and WeatherXM aims to fill these gaps by placing audited sensors in key areas, ensuring that farmers and local authorities have access to accurate and timely weather information. The deployment process was divided into three phases, starting with site preparation and connectivity audits, followed by the installation of the weather stations, and concluding with training sessions for local stakeholders on how to utilize the data effectively. With the new infrastructure in place, farmers can now access real-time weather data, enabling them to optimize their agricultural practices. This project not only enhances food security but also serves as a model for future initiatives that leverage technology to address local challenges in agriculture and disaster management.

In a significant move within the cryptocurrency landscape, two biotech firms are set to launch new Digital Asset Treasuries (DATs) after successfully raising a combined total of $402 million in private placements. These funds will be utilized to acquire substantial amounts of Aethir (ATH) and Binance Coin (BNB). The first firm, Predictive Oncology, has raised approximately $344.4 million, making it the first Nasdaq-listed company to stack Decentralized Physical Infrastructure Network (DePIN) tokens. Aethir, the second firm, focuses on providing GPU-as-a-service solutions for AI, gaming, and cloud workloads, positioning itself as a pivotal player in the decentralized infrastructure space. Dan Wang, co-founder and CEO of Aethir, highlighted the partnership's significance, referring to it as the establishment of the world’s first Strategic Compute Reserve. This initiative not only positions Aethir as a digital asset treasury but also enhances its operational capabilities to support a global infrastructure layer for AI. The investment structure includes two concurrent private placements, one involving cash investments and the other in-kind contributions of ATH, which will expedite Aethir's access to its business-focused GPU AI infrastructure. In addition to Aethir, Applied DNA Sciences is pivoting to become a BNB DAT with an allocation of up to $58 million for private investment in public equity. The firm plans to change its ticker to BNBX and has already secured $27 million in commitments, with potential for an additional $31 million. This strategy involves integrating actively managed decentralized finance protocols and Binance ecosystem-specific strategies, marking a shift from traditional passive staking methods. As the third publicly listed BNB DAT, Applied DNA Sciences aims to drive superior cash flow and returns while maintaining the flexibility and transparency that institutional investors require.

Predictive Oncology Inc. (Nasdaq: POAI), an AI-driven healthcare company, has announced a significant shift in its financial strategy by adopting a digital asset treasury (DAT) approach. This strategy, revealed on September 29, involves holding a substantial amount of cryptocurrencies on its balance sheet, akin to traditional cash or commodities holdings. The company has successfully raised approximately $344.4 million through two private investment in public equity (PIPE) transactions, earmarked for creating a DAT focused on the ATH cryptocurrency, which is the native token of Aethir, a decentralized physical infrastructure network (DePIN). A DePIN allows users to collaboratively build and operate real-world infrastructure, such as computing power and cloud services, without relying on centralized entities. The partnership with Aethir is seen as a pivotal moment for Predictive Oncology. CEO Raymond Vennare emphasized that this collaboration not only solidifies the company's core business but also opens new avenues for growth through the digital asset treasury strategy. Aethir's co-founder, Dan Wang, highlighted that Predictive Oncology's planned ATH holdings will enable it to operate within the Aethir ecosystem, enhancing Aethir's capability to provide essential infrastructure for future AI applications. This strategic move aligns with the growing trend of companies integrating cryptocurrencies into their financial frameworks, reflecting a broader acceptance of digital assets in various sectors. Following the announcement, Predictive Oncology's stock experienced a dramatic surge, opening at $2.1350 on September 29, a staggering increase of nearly 199% from its previous close of $0.7750. However, this rally was short-lived, with the stock price correcting to $1.34 shortly thereafter. Meanwhile, the ATH token has seen a remarkable rise of over 75% in the past month, trading at approximately $0.05491. Aethir also reported record-breaking revenue, earning around $13 million in both July and August, and projecting continued growth into the next quarter, showcasing the potential of the DePIN model in the evolving landscape of digital assets and AI-driven technologies.

In a groundbreaking move, a Nasdaq-listed biotech company has committed approximately $344 million to Aethir’s ATH token, marking a significant milestone as the first public U.S. company to hold and actively manage a decentralized physical infrastructure network (DePIN) token as a balance-sheet asset. This strategic financing is structured to create a "Strategic Compute Reserve" anchored in decentralized GPU infrastructure, combining a $51.7 million cash private investment in public equity (PIPE) with a crypto PIPE tied to around $292.7 million in ATH contributed in-kind. The net proceeds will be used for open-market ATH purchases, with a unique incentive where every market buy earns a 20% token grant from Aethir’s DCI Foundation. The closing of this deal is expected around October 2, pending standard approvals. Aethir is positioning ATH as the backbone of its GPU cloud services for artificial intelligence (AI) and gaming, boasting approximately 435,000 GPU containers deployed across over 200 sites in 93 countries, including support for Nvidia’s H-class chips. Despite ATH trading under $0.06 recently, the token experienced a -13% price drop after an earlier surge, leading some traders to view it as a buying opportunity. Predictive Oncology's CEO, Raymond Vennare, emphasized the strategic importance of this partnership, linking it to the company’s AI-driven drug discovery initiatives. Aethir co-founder Dan Wang referred to this initiative as the world’s first "Strategic Compute Reserve," allowing Predictive Oncology to operate directly within Aethir’s ecosystem. In addition to the ATH developments, the PepeNode project has emerged as the first meme coin virtual mining initiative, transforming traditional energy-intensive mining into a gamified experience. Currently in its presale stage, PepeNode has raised $1.5 million, with tokens priced at $0.0010788. This innovative model allows investors to build virtual mining setups and earn popular meme coins like Pepe and Fartcoin. The project’s deflationary tokenomics, where 70% of spent tokens are permanently burned upon upgrades, is designed to enhance the token’s value over time. With its smart contract audited by Coinsult, PepeNode aims to provide a secure and engaging mining experience for early adopters.

As the altcoin season progresses, traders are witnessing a shift in liquidity towards tokens that demonstrate both trading depth and specific catalysts. Unlike a broad rally across the entire sector, the current market dynamics are favoring assets linked to infrastructure, derivatives, and gaming platforms. Notable tokens such as Aethir, Mantle, and Hyperliquid have emerged as focal points, each driven by unique factors contributing to their recent price movements. This rotation exemplifies the wave-like nature of altseason, where traders seek out names with active order books and compelling narratives. Aethir (ATH) has recently gained traction, trading near $0.06 with a daily volume exceeding $110 million and a market capitalization of approximately $742 million. The token's circulating supply is around 12.2 billion out of a maximum of 42 billion. Aethir's price has appreciated by about 7% in the past day, bolstered by liquidity influx into centralized exchanges. The surge in trading activity positions Aethir as a viable candidate for short-term allocations during altseason, particularly due to its infrastructure role in gaming and cloud services, which enhances its visibility and turnover. Mantle (MNT) is also making waves, trading at around $1.69 with a market cap nearing $5.5 billion and a daily turnover surpassing $500 million. The circulating supply stands at about 3.25 billion MNT. The token's recent 5% price increase is attributed to robust exchange support and its recognition as a Layer-2 scaling solution. Meanwhile, Hyperliquid (HYPE), trading near $43 with a daily volume between $650 million and $700 million, is experiencing heightened interest due to speculation surrounding a potential spot ETF filing by Bitwise. This combination of trading activity and institutional interest keeps these tokens at the forefront of traders' minds as altseason unfolds.

In July 2025, IoTeX unveiled an ambitious roadmap aimed at constructing an AI infrastructure stack that leverages decentralized physical infrastructure network (DePIN) data. This stack encompasses various modules including L1 for execution, W3bstream for offchain proofs, ioID for device identity, Quicksilver for data aggregation, and Realms for domain-specific intelligence. Notably, the number of ioID device owners surged by 1,697% year-over-year, highlighting a growing demand for onchain device identification. The partnership with EV battery management company U Power and telecom giant Vodafone further signifies IoTeX's commitment to integrating its technology into real-world applications, such as battery-swapping stations and cell tower registrations onchain. The IoTeX platform is designed to support a wide array of applications within a decentralized ecosystem, where connected devices provide verified data for AI applications. The introduction of the Realms module aims to enhance the contextual understanding of data by organizing it into sector-specific intelligence bases. This allows AI agents to access frequently updated, verified data, which is crucial for applications in mobility, healthcare, and energy sectors. The average daily requests for Quicksilver increased by 291% month-over-month, indicating a rising interest in utilizing verified data for AI-driven solutions. IoTeX's unique architecture combines identity verification, data integrity, and agent execution, positioning it as a pivotal player in the AI landscape. The platform's native token, IOTX, plays a crucial role in governance and transaction processing within the network. With strategic partnerships and a clear roadmap, IoTeX is poised to expand its influence in the AI and DePIN sectors, catering to builders and developers who require reliable machine data and context-rich inputs for their applications.