Latest DePIN Funding News

In a groundbreaking move, a Nasdaq-listed biotech company has committed approximately $344 million to Aethir’s ATH token, marking a significant milestone as the first public U.S. company to hold and actively manage a decentralized physical infrastructure network (DePIN) token as a balance-sheet asset. This strategic financing is structured to create a "Strategic Compute Reserve" anchored in decentralized GPU infrastructure, combining a $51.7 million cash private investment in public equity (PIPE) with a crypto PIPE tied to around $292.7 million in ATH contributed in-kind. The net proceeds will be used for open-market ATH purchases, with a unique incentive where every market buy earns a 20% token grant from Aethir’s DCI Foundation. The closing of this deal is expected around October 2, pending standard approvals. Aethir is positioning ATH as the backbone of its GPU cloud services for artificial intelligence (AI) and gaming, boasting approximately 435,000 GPU containers deployed across over 200 sites in 93 countries, including support for Nvidia’s H-class chips. Despite ATH trading under $0.06 recently, the token experienced a -13% price drop after an earlier surge, leading some traders to view it as a buying opportunity. Predictive Oncology's CEO, Raymond Vennare, emphasized the strategic importance of this partnership, linking it to the company’s AI-driven drug discovery initiatives. Aethir co-founder Dan Wang referred to this initiative as the world’s first "Strategic Compute Reserve," allowing Predictive Oncology to operate directly within Aethir’s ecosystem. In addition to the ATH developments, the PepeNode project has emerged as the first meme coin virtual mining initiative, transforming traditional energy-intensive mining into a gamified experience. Currently in its presale stage, PepeNode has raised $1.5 million, with tokens priced at $0.0010788. This innovative model allows investors to build virtual mining setups and earn popular meme coins like Pepe and Fartcoin. The project’s deflationary tokenomics, where 70% of spent tokens are permanently burned upon upgrades, is designed to enhance the token’s value over time. With its smart contract audited by Coinsult, PepeNode aims to provide a secure and engaging mining experience for early adopters.

Predictive Oncology Inc. (Nasdaq: POAI), an AI-driven healthcare company, has announced a significant shift in its financial strategy by adopting a digital asset treasury (DAT) approach. This strategy, revealed on September 29, involves holding a substantial amount of cryptocurrencies on its balance sheet, akin to traditional cash or commodities holdings. The company has successfully raised approximately $344.4 million through two private investment in public equity (PIPE) transactions, earmarked for creating a DAT focused on the ATH cryptocurrency, which is the native token of Aethir, a decentralized physical infrastructure network (DePIN). A DePIN allows users to collaboratively build and operate real-world infrastructure, such as computing power and cloud services, without relying on centralized entities. The partnership with Aethir is seen as a pivotal moment for Predictive Oncology. CEO Raymond Vennare emphasized that this collaboration not only solidifies the company's core business but also opens new avenues for growth through the digital asset treasury strategy. Aethir's co-founder, Dan Wang, highlighted that Predictive Oncology's planned ATH holdings will enable it to operate within the Aethir ecosystem, enhancing Aethir's capability to provide essential infrastructure for future AI applications. This strategic move aligns with the growing trend of companies integrating cryptocurrencies into their financial frameworks, reflecting a broader acceptance of digital assets in various sectors. Following the announcement, Predictive Oncology's stock experienced a dramatic surge, opening at $2.1350 on September 29, a staggering increase of nearly 199% from its previous close of $0.7750. However, this rally was short-lived, with the stock price correcting to $1.34 shortly thereafter. Meanwhile, the ATH token has seen a remarkable rise of over 75% in the past month, trading at approximately $0.05491. Aethir also reported record-breaking revenue, earning around $13 million in both July and August, and projecting continued growth into the next quarter, showcasing the potential of the DePIN model in the evolving landscape of digital assets and AI-driven technologies.

As the altcoin season progresses, traders are witnessing a shift in liquidity towards tokens that demonstrate both trading depth and specific catalysts. Unlike a broad rally across the entire sector, the current market dynamics are favoring assets linked to infrastructure, derivatives, and gaming platforms. Notable tokens such as Aethir, Mantle, and Hyperliquid have emerged as focal points, each driven by unique factors contributing to their recent price movements. This rotation exemplifies the wave-like nature of altseason, where traders seek out names with active order books and compelling narratives. Aethir (ATH) has recently gained traction, trading near $0.06 with a daily volume exceeding $110 million and a market capitalization of approximately $742 million. The token's circulating supply is around 12.2 billion out of a maximum of 42 billion. Aethir's price has appreciated by about 7% in the past day, bolstered by liquidity influx into centralized exchanges. The surge in trading activity positions Aethir as a viable candidate for short-term allocations during altseason, particularly due to its infrastructure role in gaming and cloud services, which enhances its visibility and turnover. Mantle (MNT) is also making waves, trading at around $1.69 with a market cap nearing $5.5 billion and a daily turnover surpassing $500 million. The circulating supply stands at about 3.25 billion MNT. The token's recent 5% price increase is attributed to robust exchange support and its recognition as a Layer-2 scaling solution. Meanwhile, Hyperliquid (HYPE), trading near $43 with a daily volume between $650 million and $700 million, is experiencing heightened interest due to speculation surrounding a potential spot ETF filing by Bitwise. This combination of trading activity and institutional interest keeps these tokens at the forefront of traders' minds as altseason unfolds.

In July 2025, IoTeX unveiled an ambitious roadmap aimed at constructing an AI infrastructure stack that leverages decentralized physical infrastructure network (DePIN) data. This stack encompasses various modules including L1 for execution, W3bstream for offchain proofs, ioID for device identity, Quicksilver for data aggregation, and Realms for domain-specific intelligence. Notably, the number of ioID device owners surged by 1,697% year-over-year, highlighting a growing demand for onchain device identification. The partnership with EV battery management company U Power and telecom giant Vodafone further signifies IoTeX's commitment to integrating its technology into real-world applications, such as battery-swapping stations and cell tower registrations onchain. The IoTeX platform is designed to support a wide array of applications within a decentralized ecosystem, where connected devices provide verified data for AI applications. The introduction of the Realms module aims to enhance the contextual understanding of data by organizing it into sector-specific intelligence bases. This allows AI agents to access frequently updated, verified data, which is crucial for applications in mobility, healthcare, and energy sectors. The average daily requests for Quicksilver increased by 291% month-over-month, indicating a rising interest in utilizing verified data for AI-driven solutions. IoTeX's unique architecture combines identity verification, data integrity, and agent execution, positioning it as a pivotal player in the AI landscape. The platform's native token, IOTX, plays a crucial role in governance and transaction processing within the network. With strategic partnerships and a clear roadmap, IoTeX is poised to expand its influence in the AI and DePIN sectors, catering to builders and developers who require reliable machine data and context-rich inputs for their applications.

Nosana, a decentralized GPU marketplace, has reached a significant milestone by surpassing 50,000 independent GPU hosts since the mainnet launch in January 2025. This achievement comes amid a resurgence in the crypto market, with the NOS token experiencing a 5.3% increase, reaching $0.7523. The platform, built on Solana's high-speed blockchain, democratizes access to GPU resources, allowing everyday hardware owners to monetize their unused devices by renting them out for AI workloads. This model not only provides developers with affordable computing power but also creates a new income stream for hardware owners, marking a pivotal moment in the intersection of blockchain and artificial intelligence. The recent surge in NOS's value reflects a broader trend as the token gains traction among both retail and institutional investors. Trading volumes on major exchanges like MEXC and Bybit have increased significantly, indicating rising liquidity and interest in AI-focused projects. Analysts predict that NOS could continue its upward trajectory, potentially reaching $0.82 by early October, driven by seasonal factors and the growing demand for decentralized AI computing solutions. The platform's unique utility-based model positions it favorably against the backdrop of a struggling altcoin market, providing a buffer against macroeconomic challenges. Nosana's community is thriving, with developers actively engaging in discussions about the platform's capabilities and success stories. The decentralized nature of the project fosters collaboration and innovation, enabling users to leverage their hardware for AI tasks without significant upfront investments. As the platform continues to evolve, it aims to expand its support for medium-sized businesses and enhance its governance structure. With promising forecasts for the future, including potential price targets of $1.07 by year-end and $3.50 by 2030, Nosana is poised to play a crucial role in the AI compute landscape, transforming everyday technology into powerful resources for innovation.

Seoul, South Korea, is set to host the AI DePIN RWA Day during the Korea Blockchain Week 2025 on September 25, 2025. This four-hour event, running from 10 AM to 2 PM, aims to unite builders, investors, and innovators who are at the forefront of decentralized technologies. The event is strategically aligned with KBW Asia's premier blockchain conference, focusing on three transformative verticals in Web3: Artificial Intelligence (AI), Decentralized Physical Infrastructure (DePIN), and Real-World Assets (RWA). This convergence promises to showcase the latest advancements and insights in these rapidly evolving fields. The event is hosted by prominent organizations including Io.net, FailSafe, and ForkOff. Io.net is recognized as a leading decentralized GPU network that provides scalable infrastructure for AI and blockchain applications. FailSafe, backed by Sequoia and Dragonfly Capital, specializes in security services for blockchain companies, offering audits and risk monitoring. ForkOff, a culture studio, focuses on amplifying narratives and creating impactful experiences within the blockchain ecosystem. Together, these hosts represent critical pillars of Web3, emphasizing security, infrastructure, and culture. Attendees can expect a rich agenda featuring keynotes and discussions that delve into how AI, DePIN, and RWA are reshaping infrastructure and finance. There will also be opportunities for networking among investors, developers, and operators, fostering a collaborative atmosphere. With strategic partnerships from Taiko, Tectonic, Sogni Protocol, and Camp Network, the AI DePIN RWA Day aims to promote mainstream adoption and cultural integration within the Web3 space, making it a highlight of the Korea Blockchain Week 2025.

Helium has emerged as a frontrunner in the Decentralized Physical Infrastructure Network (DePIN) sector, particularly following its recent partnership with the Solana Seeker mobile phone. This collaboration has significantly boosted Helium's fee generation, contributing to a remarkable increase in overall activity within the DePIN space. Over the past month, the sector has seen fees reach unprecedented levels, with Helium alone generating between $330,000 and $370,000 weekly, which constitutes approximately 60% of the average fee income across the market. In addition to Helium, other notable players in the DePIN sector include Geonet, Akash Network, and Hivemapper, which collectively account for about $181,000 in fees, representing 32% of the total fees produced in the last week. Despite this surge in activity and fee generation, the performance of DePIN project tokens has been disappointing. Leading tokens from projects such as Render, Filecoin, and Helium have experienced declines ranging from 40% to 70% over the past year, indicating a significant disconnect between the operational success of these projects and their market valuations. The contrasting trends in fee generation and token performance highlight the challenges faced by the DePIN sector. While the infrastructure and usage of decentralized networks are growing, the market sentiment surrounding these tokens remains bearish. This situation raises questions about the future of DePIN projects and their ability to translate operational success into positive market performance, as investors remain cautious amidst ongoing volatility in the cryptocurrency landscape.

Theta Network continues to set the standard in decentralized streaming with its innovative dual-token model. THETA serves as the governance and staking token, while TFUEL is utilized for content delivery. This system enables users to contribute their bandwidth and computing resources through Edge Nodes, earning rewards in return. By decentralizing infrastructure demands, Theta not only reduces costs for platforms but also enhances efficiency compared to traditional centralized Content Delivery Networks (CDNs). The project has garnered significant partnerships with major companies like Samsung and Sony, further solidifying its position as a leader in blockchain-based media infrastructure. By 2025, Theta's technology is expected to extend beyond video streaming, incorporating gaming, virtual reality, and artificial intelligence workloads. In contrast, XRP Tundra has introduced a presale model that emphasizes clarity and utility for investors. Buyers can purchase TUNDRA-S tokens on the Solana blockchain at a price of $0.01, receiving a complimentary allocation of TUNDRA-X tokens on the XRP Ledger, which serve as governance and reserve tokens. This presale is notable for its transparency, with fixed launch prices set at $2.50 for TUNDRA-S and $1.25 for TUNDRA-X. By dedicating 40% of the TUNDRA-S supply to presale buyers, participants can secure a substantial share of the ecosystem prior to secondary market listings, a rarity in the current presale landscape. Both Theta and XRP Tundra utilize dual-token systems, albeit for different purposes. Theta focuses on decentralized video delivery and partnerships with major media companies, while XRP Tundra is centered around presale economics and yield generation for XRP holders. Each project highlights the versatility of dual-token models, showcasing their application in distinct sectors—entertainment infrastructure versus financial utility. For investors, the choice between these two projects reflects a broader decision about sector engagement, illustrating how blockchain innovation can create new value in diverse markets.

Bittensor (TAO) and Ethereum (ETH) are at the forefront of discussions among market analysts, with both cryptocurrencies showing promising potential for growth. Bittensor has set ambitious targets, with predictions suggesting a possible rise to $1000, driven by its AI-focused blockchain framework. Analysts highlight the importance of decentralized intelligence markets and increasing adoption as key factors that could help TAO reach this milestone. Currently, TAO is consolidating around strong support levels, indicating steady accumulation, although volatility remains a concern. For Bittensor to realize its ambitious projections, broader adoption and participation from larger players will be crucial. Ethereum, on the other hand, continues to maintain its central role in the cryptocurrency market. Recent analysis indicates that ETH has remained stable at critical levels, with the potential for a bullish breakout if it surpasses the $4,600 mark. The increasing inflow of ETFs and a burgeoning DeFi sector are contributing to Ethereum's resilience. On-chain activity is also supportive, with a rise in active addresses and strong staking demand. However, analysts warn that a significant upward movement will require robust trading volumes, particularly above $4,700, to sustain momentum into 2025. Meanwhile, BlockDAG (BDAG) is making strides in the presale space, having raised nearly $410 million and demonstrating real adoption through the delivery of over 19,900 miner units. With a presale price fixed at $0.0013 until October 1, BlockDAG is positioning itself as a strong contender in the market. Its infrastructure and community support are evident, with features that enhance transparency and engagement. As the project prepares for its exchange launch, its focus on tangible progress sets it apart from more speculative ventures, making it a noteworthy option for investors looking to buy and mine in 2025.

CUDOS is launching an early access program that offers builders the chance to gain rewards, compute credits, and priority access to their new platform. With the deadline approaching on September 23rd, this initiative invites developers to be among the first to deploy on the platform. Participants can earn over $100,000 in rewards, including inference credits and FET token rewards based on their usage in the first three months after launch. The rewards structure is tiered, with the top 1,000 verified users on the leaderboard receiving varying amounts of credits, encouraging early adoption and engagement. The early access program is designed to provide users with significant benefits, including GPU inference from day one and the ability to climb the leaderboard through referrals. Users can earn FET tokens by spending on the platform, with additional bonuses for those already in the top 100. CUDOS is also incentivizing community involvement by offering a pool of $500 in FET to five winners who share their referral links on social media. This initiative aims to foster a sense of community and reward participation in the CUDOS ecosystem. To join the early access program, users need to verify their email and can boost their leaderboard position by referring others. The platform promises a seamless experience for early adopters, allowing them to deploy next-gen models without the usual bottlenecks. As the launch date approaches, CUDOS encourages interested parties to secure their spot and take advantage of the rewards available, emphasizing the importance of building a decentralized future for compute resources.